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目的探讨单唾液酸四已糖神经节苷酯注射液治疗急性脑梗死的疗效。方法随机选出152例急性脑梗死患者分为两组,治疗组用单唾液酸四已糖神经节苷酯注射液40mg加入NS250ml静脉滴注,1次/d,21d为1个疗程。对照组用胞二磷胆碱注射液0.75加入NS250ml静脉滴注,疗程及用法同治疗组。结果采用治疗组基本治愈率(30.5%)、总有效率(84.2%),明显高于对照组基本治愈率(18.6%)、总有效率(65.6%),两者有统计学差异(P<0.05)。结论早期应用单唾液酸四已糖神经节苷酯注射液治疗急性脑梗死,可加速神经功能的恢复,提高患者的生存质量,改善预后。
Objective To investigate the efficacy of monosialotetraosyl ganglioside injection in the treatment of acute cerebral infarction. Methods A total of 152 acute cerebral infarction patients were randomly divided into two groups. The treatment group was treated with intravenous infusion of 40mg monosialoglycans ganglioside into NS250ml once a day for 21 days. Control group with citicoline 0.75 injection NS250ml intravenous infusion, treatment and usage of the same treatment group. Results The basic cure rate (30.5%) and total effective rate (84.2%) in the treatment group were significantly higher than those in the control group (18.6%) and the total effective rate (65.6%) (P < 0.05). Conclusion The early application of monosialotetrahexosyl ganglioside injection in the treatment of acute cerebral infarction can accelerate the recovery of neurological function, improve the quality of life of patients and improve the prognosis.