Down综合征的患儿表现为:①智力低下:几乎都有此症状;②特殊面容,几乎都有睑裂小、鞍鼻等;③部分有小头颅,枕部扁平;④眼症状,白内障(约50%),眼球振颤(少数);⑤部分患儿有巨舌;⑥几乎都有短手指的特征;⑦并发先天性心脏病(约40%);⑧少数有消化道畸形,脐疝、十二指肠闭锁等;⑨并发白血病(约1%);⑩并发唇裂和腭裂(约0.5%);⑾少数有肌张力减低。作者们于1973年对长崎县立久原养护学校(译者注:专收智力低下或患病儿童的学校)小学、中学部在校学生73人进行检查,有18人为Down综合征,其中合并慢性鼻窦炎者7人。对此7人令其自行鼻腔冲洗治疗,每天一次,每周到医院检查一次。治疗时间最短5个月,最长5年5个月。结果:仅1例有效,3例微效。7例患儿作了鼻窦X线照相检查(瓦氏位及 Down syndrome patients showed: ① mental retardation: Almost all have this symptom; ② special face, almost all palpebral fissure, saddle nose and so on; ③ some small skull, occipital flat; ④ ocular symptoms, cataract About 40%); ⑧ a small number of digestive tract malformations, umbilical hernia, umbilical cord, Duodenal atresia, etc .; ⑨ concurrent leukemia (about 1%); ⑩ complicated cleft lip and cleft palate (about 0.5%); ⑾ a small number of muscle tension decreased. The authors examined 73 students in primary and secondary schools in Nagasaki Prefectural Kyushu Conservation School in 1973, and 18 of them were Down Syndromes, of which the merger Chronic sinusitis in 7 people. This 7 people make their own nasal irrigation treatment, once a day, to the hospital once a week. The shortest treatment time of 5 months, up to 5 years and 5 months. Results: Only 1 case was effective and 3 cases were ineffective. Seven children underwent sinus radiography (Valsalva)