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目的 :探讨心脏肌钙蛋白 (c Tn )在急性心肌梗死 (AMI)中的临床意义。方法 :6 0例 AMI,其中 Q波型 AMI42例 ,非 Q波型 AMI18例 ,分别于入院即刻、 2 4小时、 72小时、 7天抽血 ,测定 c Tn 、CK- MB,随访半年。结果 :(1) c Tn 阳性率在 AMI即刻、 2 4小时、 72小时、 7天的 Q波型 AMI和非 Q波型 AMI依次分别为2 3.8% ,10 0 % ,90 .48% ,2 6 .19% ;11.11% ,77.78% ,5 5 .5 6 % ,16 .6 1%。Q波型 AMI的 c Tn 水平明显依次高于 CK- MB的 11.9%、 90 .48%、 11.97%、 0 % ;(2 )第 7天持续阳性的 14例中 ,4例死于心脏骤停 ,5例发生心衰 ,5例发生心绞痛。结论 :(1) AMI后 2 4小时 c Tn 阳性率高于 CK- MB;(2 ) c Tn 阳性持续者预后不佳
Objective: To investigate the clinical significance of cardiac troponin (cTn) in acute myocardial infarction (AMI). Methods: Sixty AMI patients, including Q-wave AMI in 42 cases and non-Q-wave AMI in 18 cases, were drawn on admission, 24 hours, 72 hours and 7 days respectively. The levels of cTn and CK-MB were measured and followed up for six months. Results: (1) The positive rates of cTn were 23.8%, 100%, 90.48% and 2% respectively at AMI, 24 hours, 72 hours and 7 days after AMI and non-Q AMI 6.19%, 11.11%, 77.78%, 55.5%, 16.61%. The level of cTn in Q-wave AMI was significantly higher than that of CK-MB in 11.9%, 90.48%, 11.97% and 0%, respectively. (2) Of the 14 patients who were positive on the 7th day, 4 died of cardiac arrest , 5 cases of heart failure, angina pectoris in 5 cases. Conclusions: (1) The positive rate of cTn in 24 hours after AMI was higher than CK-MB. (2) The prognosis of cTn positive persistence was poor