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用激光多普勒微循环血流计研究多巴胺对失血性休克大鼠及家兔肾微循环血液灌流量的影响,并对其机制作初步探讨。 方法与结果 雄性Wistar大鼠32只,体重200～250g,麻醉后颈动脉测血压,打开腹腔,用LDF-2型激光多普勒微循环血流计测肾、肝、脾、尾表面固定部位的血流量。血流计探头直径1mm,灌流量用电压(V)表示。用常规方法复制失血性休克,血压维持在
The effect of dopamine on hepatic microcirculatory blood perfusion in hemorrhagic shock rats and rabbits was studied with a laser Doppler microcirculatory flow meter, and its mechanism was discussed. Methods and Results Thirty-two male Wistar rats weighing 200-250 g, anesthetized with carotid artery, and blood pressure were measured. The abdominal cavity was opened. The LDF-2 laser Doppler microcirculatory blood flow was used to measure the fixed sites of the kidney, liver, spleen and tail. Blood flow. The blood flow meter probe diameter is 1mm, and the perfusion flow is expressed by the voltage (V). Hemorrhagic shock is replicated by conventional methods and blood pressure is maintained