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目的：比较布洛芬缓释胶囊与吲哚美辛治疗急性风湿性关节炎的疗效。方法：７２例急性风湿性关节炎病人分２组，３６例（男性１９例，女性１７例，年龄３２±ｓ７ａ）用布洛芬缓释胶囊６００ｍｇ，ｐｏ，ｂｉｄ；另３６例（男性２０例，女性１６例，年龄３１±９ａ）用吲哚美辛５０ｍｇ，ｐｏ，ｔｉｄ，２组均经３ｗｋ治疗。结果：布洛芬缓释胶囊和吲哚美辛的有效率分别为９５％和７０％，有显著差异Ｐ＜０．０５。消化道副作用布洛芬缓释胶囊较吲哚美辛为少。结论：布洛芬缓释胶囊治疗急性风湿性关节炎的疗效明显高于吲哚美。
Objective: To compare the efficacy of ibuprofen sustained-release capsules and indomethacin in the treatment of acute rheumatoid arthritis. Methods: Seventy-two patients with acute rheumatoid arthritis were divided into two groups, 36 patients (19 males, 17 females, age 32 ± s7a) with ibuprofen sustained release capsules 600mg, po, bid; the other 36 patients (20 males , 16 females, age 31 ± 9a) with indomethacin 50mg, po, tid, 2 groups were treated 3wk. Results: The effective rates of ibuprofen sustained release capsules and indomethacin were 95% and 70%, respectively, with a significant difference P <0.05. Side effects of ibuprofen ibuprofen sustained release capsules are less than indomethacin. Conclusion: The efficacy of ibuprofen sustained release capsules in the treatment of acute rheumatoid arthritis is significantly higher than indomethacin.