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透明质酸(HA)是测定肝功能的敏感指标之一。我们应用放射免疫分析(RIA)法测定258例肝病患者及117例正常人血清HA含量,以探讨HA在肝病诊断中的价值。 对象和方法 一、对象:正常人对照组117例(男81,女36)。年龄20～58岁,经检查无心、肝、肾等疾病的健康查体人群。肝病组258例(男177,女81),均为我院传染科和消化内科的住院及门诊病人,年龄21～68岁。其中急性肝炎(AH)108例,慢性迁延性肝炎(CPH)75例,慢性活动性肝炎(CAH)45例,肝硬化(LC)30例。诊断标准均按第六届全国病毒性肝炎会议修订标准确诊。
Hyaluronic acid (HA) is one of the sensitive indicators of liver function. We used radioimmunoassay (RIA) method to determine the serum HA levels in 258 patients with liver disease and 117 normal subjects to explore the value of HA in the diagnosis of liver disease. Objects and methods First, the object: normal control group of 117 cases (male 81, female 36). Aged 20 to 58 years old, check the heartless, liver, kidney and other health check-up crowd. 258 cases of liver disease (male 177, female 81), are hospital inpatient and outpatient department of Infectious Diseases and Gastroenterology, aged 21 to 68 years. There were 108 cases of acute hepatitis (AH), 75 cases of chronic persistent hepatitis (CPH), 45 cases of chronic active hepatitis (CAH) and 30 cases of liver cirrhosis (LC). Diagnostic criteria were confirmed according to the revised standards of the Sixth National Viral Hepatitis Meeting.