幽门螺杆菌(Hp)感染率在西方国家是20%~50%,发展中国家是80%。Hp与胃炎、消化性溃疡、胃癌等上消化道疾病的发生有关。此外,还与其他肠外疾病包括特发性血小板减少性紫癜、不明原因的缺铁性贫血、胰岛素抵抗(代谢综合征)及慢性特发性荨麻疹密切相关~[1]。有报道,1983—1997年Hp平均根除率为75%~90%,1996—2005年下降 Helicobacter pylori (Hp) infection rates are 20% to 50% in Western countries and 80% in developing countries. Hp and gastritis, peptic ulcer, stomach cancer and other upper gastrointestinal diseases. In addition, it is also closely related to other parenteral diseases including idiopathic thrombocytopenic purpura, unexplained iron deficiency anemia, insulin resistance (metabolic syndrome) and chronic idiopathic urticaria. [1] It has been reported that the average Hp eradication rate was between 75% and 90% from 1983 to 1997 and from 1996 to 2005