一、前言 DM423菌株是一种需氧芽胞杆菌,经我院正常菌群研究组及中国科学院微生物研究所鉴定为蜡样芽胞杆菌。该菌在试管内或动物体内表现具有促进正常肠菌群的厌氧菌成员,特别是双歧杆菌的生长繁殖作用。利用这一特性,我院正常菌群研究组,根据初步的毒性试验结果,曾在临床上进行了一些初步观察。观察结果指出,该菌的活菌制剂“促菌生”,对婴幼儿腹泻及其它肠道病具有一定疗效。因 I. INTRODUCTION The DM423 strain is a kind of aerobic Bacillus. It was identified as Bacillus cereus by the normal flora research group of our hospital and the Institute of Microbiology of the Chinese Academy of Sciences. The bacterium exhibits the anaerobic bacteria members that promote normal intestinal flora, particularly the growth and reproduction of Bifidobacteria, in vitro or in vivo. Utilizing this feature, the normal flora group of our hospital has conducted some preliminary observations in clinical trials based on the results of preliminary toxicity tests. Observations indicate that the live bacteria preparation of the bacterium “promotes bacterial growth” has a certain effect on infant diarrhea and other intestinal diseases. because