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目的:从初生物质含量变化的角度探究黄连-肉桂药对配伍前后药性的改变。方法:总糖含量测定采用费林氏容量法,总蛋白含量测定采用考马斯亮蓝法,总脂肪含量测定采用连续回流提取法及重量法。用秩和检验及t检验分析实验结果。结果:黄连、肉桂与其药对的初生物质含量有明显的差异,三者间比较,结果具有统计学意义(P<0.05);黄连-肉桂药对组分别与黄连、肉桂组比较,初生物质含量有明显的差异,结果同样具有统计学意义(P<0.0167)。结论:黄连-肉桂药对配伍之后,寒热药性发生了变化。
Objective: To explore the changes of the pharmacological effects of berberine - cinnamon before and after the compatibility from the perspective of the change of the content of primary biomass. Methods: The total sugar content was determined by Fehling’s volumetric method, the total protein content was determined by Coomassie brilliant blue method, the total fat content was determined by continuous reflux extraction method and gravimetric method. The rank sum test and t test were used to analyze the experimental results. Results: There was a significant difference in the content of primary biomass of Coptis chinensis, Cinnamon and their medicine, and the results were statistically significant (P <0.05). Compared with Coptis chinensis and Cinnamon, There were significant differences and the results were also statistically significant (P <0.0167). Conclusion: Coptis - cinnamon drug compatibility, cold and heat medicine has changed.