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目的了解云南省德宏州HIV感染者中病情长期不进展者(long-term nonprogressors,LTNP)所占的比例及其影响因素。方法在国家“艾滋病综合防治数据信息管理系统”中下载1989年至2011年12月31日的历史卡片,选取其中报告时间≥15年、现住址和户籍均为云南省德宏州(不包含查无此人)的所有HIV感染者作为研究对象。结果符合入选标准的研究对象共1 461人,其中有90人(6.2%)根据严格定义归类为LTNP。多因素Logistic回归分析显示:不同年龄、地区、婚姻状况和文化程度的HIV感染者中病情LTNP所占比例不同,HIV感染者中LTNP所占比例以≤19岁、未婚、初中及以上文化程度者中较高,而在陇川县较低。结论云南省德宏州HIV感染者中存在一定比例的病情长期不进展者,且与其社会人口学特征显著相关,值得进一步深入研究。
Objective To investigate the proportion of long-term nonprogressors (LTNP) and its influencing factors among HIV-infected people in Dehong Prefecture of Yunnan Province. Methods The historical card from 1989 to December 31, 2011 was downloaded from the National Integrated AIDS Prevention and Control Information System. The report card was selected for more than 15 years. The current address and household registration were both in Dehong Prefecture of Yunnan Province Including the absence of such people) of all HIV-infected subjects as the study. Results A total of 1,461 subjects met the inclusion criteria, of whom 90 (6.2%) were classified as LTNP by strict definition. Multivariate logistic regression analysis showed that the proportion of LTNP among HIV-infected persons of different age, region, marital status and education level was different, and the proportion of LTNP in HIV-infected persons was ≤19 years old, unmarried, middle school and above In the higher, while lower in Longchuan County. Conclusions There is a certain proportion of HIV-infected persons in Dehong Prefecture of Yunnan Province, whose long-term progression is not progressing, which is significantly related to their socio-demographic characteristics and deserves further study.