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对23例急性心肌梗塞(AMI)、23例不稳定型心绞痛(UA)及20例正常人的血浆β-血小板球蛋白(β-TG)和血小板第4因子(PF_4)含量进行测定,并观察运动试验对部分冠心病患者和正常人的血浆β-TG和PF_4含量的影响。结果表明,AMI和UA患者的血浆β-TG和PF_4含量显著高于正常人,其中AMI患者的β-TG还显著高于UA患者,在运动试验前、后血浆β-TG和PF_4含量无显著差异。提示冠心病患者在急性心肌缺血发作时,血小板释放反应增加,活性增强,其发生机理与血栓形成关系密切,此可为冠心病患者临床应用抗血小板药提供依据。
The levels of plasma beta-thromboglobulin (β-TG) and platelet factor 4 (PF_4) in 23 patients with acute myocardial infarction (AMI), 23 patients with unstable angina pectoris (UA) and 20 normal subjects were measured and observed Effect of Exercise Test on Plasma β-TG and PF_4 Contents in Some Coronary Heart Disease Patients and Normal People. The results showed that the levels of plasma β-TG and PF_4 in patients with AMI and UA were significantly higher than those in normal subjects. The β-TG in patients with AMI was significantly higher than that in patients with UA. There was no significant difference in plasma β-TG and PF_4 before and after exercise test difference. Prompted coronary heart disease in patients with acute myocardial ischemia, the platelet release response increased, the activity increased, and its pathogenesis and thrombosis are closely related, which can provide clinical evidence for the clinical application of antiplatelet drugs.