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一般来说胎儿出生数分钟后,动脉导管机能上自行关闭,但最后完全闭合常在生后3～4个月,一岁后仍未闭者即为畸形。本畸形为常见先心病之一,约占先心病总数的12％。一、胚胎学:胚胎5～7周,从大动脉发出6对动脉弓,左第4弓演变成主动脉弓,左、右第6弓分别发出分支形成左右肺动脉,右6弓远端退化消失,左6弓远端形成动脉导管,连接肺动脉和主动脉。出生后动脉导管自然闭合成为大动脉韧带。关于动脉导管自然闭合机理有如下几种说法: 1.动脉导管在组织结构上与主动脉,肺动脉不同,其肌层丰富,富有弹性纤维,内壁皱
In general, a few minutes after the birth of the fetus, the ductus arteriosus itself closed, but the final complete closure is often 3 to 4 months after birth, one year old still have not closed who is deformed. The deformity is one of the common congenital heart disease, accounting for about 12% of the total number of congenital heart disease. Embryology: embryos from 5 to 7 weeks, from the aortic artery issued 6 pairs of arches, left 4 arch evolved into the aortic arch, the left and right 6th bow were branched into the left and right pulmonary artery, right 6 bow distal degradation disappeared, the left 6 The distal bow forms a ductus arteriosus connecting the pulmonary and aorta. After birth, the patent ductus arteriosus naturally becomes the aorta ligament. On the natural closure of the patent ductus arteriosus has the following statement: 1. The structure of the ductus arteriosus and aorta, pulmonary artery is different, the muscular layer is rich in elastic fibers, the inner wall wrinkles