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目的探讨致心律失常性右室心肌病(ARVD/C)高危患者相关危险因素。方法根据1994年ARVD/C诊断标准,纳入43例ARVD/C先证者。分组标准:有晕厥病史并记录到室性心动过速(简称室速)为高危病人;记录到室性早搏(简称室早)、室速但无晕厥病史及其他临床情况定为低危病人。收集参数包括:①心电图V1～3QRS波时限≥110 ms、V1～3导联S波升支时限≥55 ms、Epsilon波、T波倒置、(V1+V2+V3)/(V4+V5+V6)QRS波时限≥1.2、QRS波离散度≥40 ms、QT离散度≥65 ms;②信号平均心电图记录晚电位参数;③Holter记录室早或室速;④超声记录双房、双室及右室流出道、流入道内径大小。Logistic回归分析高危患者ARVD/C病人的相关危险因素。结果心室晚电位阳性、右室射血分数<0.40与高危ARVD/C显著相关。结论晚电位阳性、右心功能不全是ARVD/C的高危因素。
Objective To explore the risk factors associated with high-risk patients with arrhythmogenic right ventricular cardiomyopathy (ARVD / C). Methods Based on the 1994 ARVD / C diagnostic criteria, 43 ARVD / C probands were enrolled. Grouping criteria: a history of syncope and recorded ventricular tachycardia (referred to ventricular tachycardia) as high-risk patients; recorded ventricular premature beats (referred to as ventricular premature), ventricular tachycardia, but no history of syncope and other clinical conditions as low-risk patients. Collecting parameters include: ① ECG V1 ~ 3QRS wave duration ≥110 ms, V1 ~ 3 lead S wave rise time ≥55 ms, Epsilon wave, T wave inversion, (V1 + V2 + V3) / (V4 + V5 + V6 ) QRS wave duration ≥1.2, QRS wave dispersion ≥40 ms, QT dispersion ≥65 ms; ② signal average ECG recording late potential parameters; ③ Holter recording room early or ventricular rate; ④ ultrasound recording of double room, double room and right room Outflow Road, the size of the inflow Road diameter. Logistic regression analysis of risk factors for ARVD / C patients at high risk. Results The ventricular late potential positive, right ventricular ejection fraction <0.40 and high risk ARVD / C was significantly correlated. Conclusions Positive posterior potential and right ventricular dysfunction are risk factors of ARVD / C.