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目的探讨恶性肿瘤患者梅毒TP(Treponema Pallidum)感染的阳性分布趋势及其在不同肿瘤疾病中的分布情况。方法用ELISA法和TPPA法对在我院住院并确诊为恶性肿瘤的5 324例患者进行梅毒螺旋体抗体检测。结果恶性肿瘤患者梅毒螺旋体抗体阳性率为1.84%,明显高于一般人群。肿瘤患者男性感染率略高于女性,但无显著性差异。在51～70岁年龄段人数明显高于其他年龄段。不同恶性肿瘤患者TP感染的阳性率差异有统计学意义(P<0.01),以子宫内膜癌最高,其次是胰腺癌,卵巢癌等。结论恶性肿瘤患者梅毒感染的阳性率较高。建议恶性肿瘤患者住院应常规进行梅毒螺旋体检测,对预防医院感染,防止医疗纠纷具有重要意义。
Objective To investigate the positive distribution trend of Treponema Pallidum infection in patients with malignant tumor and its distribution in different tumor diseases. Methods 5 324 cases of hospitalized patients diagnosed as malignant tumors in our hospital were tested for anti-treponema pallidum antibody by ELISA and TPPA. Results The positive rate of Treponema pallidum antibody in patients with malignant tumors was 1.84%, which was significantly higher than that of the general population. Male patients with cancer infection rate slightly higher than women, but no significant difference. The number of people in the 51-70 age group was significantly higher than other age groups. The positive rates of TP infection in different malignant tumors were statistically different (P <0.01), the highest in endometrial cancer, followed by pancreatic cancer and ovarian cancer. Conclusions The positive rate of syphilis infection in patients with malignant tumors is high. Proposed hospitalization of patients with malignant tumors should be routine Treponema pallidum test, to prevent hospital infections and prevent medical disputes is of great significance.