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白细胞介素 18(ＩＬ - 18)是由活化的巨噬细胞产生的一种细胞因子。起初发现它可诱导辅助性Ｔ细胞和自然杀伤细胞 (ＮＫ)产生γ -干扰素 (ＩＦＮ -γ) ,故一度被称为ＩＦＮ -γ诱生因子 (ＩＧＩＦ)。近来诸多研究证实 :ＩＬ - 18除能强烈地诱导免疫细胞释放ＩＦＮ -γ、ＴＮＦ
Interleukin 18 (IL - 18) is a cytokine produced by activated macrophages. Initially it was found to induce IFN-γ (IFN-γ) production by helper T cells and natural killer (NK) cells and was once referred to as IFN-γ-inducing factor (IGIF). Recently, many researches confirm that IL - 18 can strongly induce immune cells to release IFN - γ, TNF