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目的评价液基细胞薄膜制片技术在宫颈病变筛查中的临床应用价值。方法对978例液基细胞(TCT)检查标本用TBS诊断系统进行分析,对意义不明确的非典型鳞状细胞(ASCUS)以上的标本患者均行阴道镜检查和病理组织活检,以病理组织活检结果为标准按照细胞学与组织学可以相差一级的国际原则进行统计其符合率。结果 978例标本中宫颈液基细胞学TBS诊断结果显示未见病变细胞者921例(94.17%),诊断阳性者32例(5.83%),原位癌2例、CIN32例、鳞状细胞癌3例、宫颈鳞状细胞上皮高度病变(CIN2)6例、宫颈鳞状细胞上皮低度病变(CIN1)12例、ASCUS者32例,鳞状细胞癌、高度病变、低度病变与病理组织活检符合率分别为100.0%、86.0%、74.6%。结论 TCT检查对宫颈癌早期和高度病变检出率较高,可用于宫颈病变的筛查。
Objective To evaluate the clinical value of liquid-based cell membrane technology in the screening of cervical lesions. Methods A total of 978 liquid-based cells (TCT) were examined by TBS diagnostic system. Colposcopy and pathological biopsy were performed on specimens of atypical squamous cell (ASCUS) of uncertain significance. Pathological biopsy Results as a standard in accordance with the cytology and histology can be a difference between the international principle of its statistical compliance rate. Results There were 921 cases (94.17%) with no pathological cells, 32 cases (5.83%) with positive diagnosis, 2 cases with carcinoma in situ, 32 cases with CIN, squamous cell carcinoma 3 Cases of cervical squamous cell epithelial lesions (CIN2) in 6 cases, cervical squamous cell epithelial lesions (CIN1) in 12 cases, ASCUS in 32 cases, squamous cell carcinoma, high grade lesions, low grade lesions consistent with the pathological biopsy Rates were 100.0%, 86.0%, 74.6% respectively. Conclusion The detection rate of TCT in early stage and high grade of cervical cancer is high, which can be used in screening cervical lesions.