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目的对CO2激光在早期声门型喉癌治疗中的应用进行临床分析和评价。方法对2011-12-2014-02在我院耳鼻喉科行CO2激光治疗的60例早期声门型喉癌患者的临床资料进行总结和分析。结果术后8例复发,复发率为13.3%(8/60)。其中,T1a病变3例,复发率为11.5%(3/26),T1b病变3例,复发率为20.0%(3/15),T2病变2例,复发率为20.0%(2/10),组间比较差异无统计学意义(χ2=0.180,P>0.05);21例患者肿瘤浸润至前联合,有7例复发,复发率为33.3%(7/21);39例患者肿瘤未浸润至前联合,有2例复发,复发率为5.1%(2/39),两组间差异有统计学意义(χ2=9.003,P<0.05)。结论 CO2激光手术治疗早期声门型喉癌疗效安全可靠,对发音功能保留好,值得在临床推广应用。
Objective To evaluate the clinical application of CO2 laser in the treatment of early glottic laryngeal cancer. Methods The clinical data of 60 patients with early glottic laryngeal cancer treated with CO2 laser in ENT department of our hospital from Dec 2011 to Feb 2014 were summarized and analyzed. Results 8 cases relapsed after surgery, the recurrence rate was 13.3% (8/60). There were 3 cases with T1a lesions, the recurrence rate was 11.5% (3/26), T1b lesions were 3 cases, the recurrence rate was 20.0% (3/15), T2 lesions were 2 cases, the recurrence rate was 20.0% (2/10) There was no significant difference between the two groups (χ2 = 0.180, P> 0.05). Tumor recurrence was found in 21 patients before relapse, with recurrence rate of 33.3% (7/21) in 21 patients. Before the combination, there were 2 cases of recurrence, the recurrence rate was 5.1% (2/39), the difference between the two groups was statistically significant (χ2 = 9.003, P <0.05). Conclusion CO2 laser surgery for the treatment of early glottic laryngeal cancer is safe and reliable, and has good retention of phonological function, which is worthy of clinical application.