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目的探讨盐酸氨溴索联合复方异丙托溴铵雾化吸入治疗毛细支气管炎的疗效。方法将70例毛细支气管炎患儿随机分为对照组和治疗组各35例,两组均给予抗炎、平喘等常规对症处理,对照组给予地塞米松、利巴韦林雾化吸入,治疗组在常规治疗基础上给予盐酸氨溴索和复方异丙托溴铵雾化吸入治疗,观察两组治疗后疗效。结果对照组和治疗组总有效率分别为74.28%、94.29%,两组比较差异有统计学意义;治疗组发热、咳嗽、哮鸣音消失及住院时间均明显短于对照组(P<0.05)。结论盐酸氨溴索联合复方异丙托溴铵雾化吸入治疗毛细支气管炎可迅速改善症状,缩短病程,疗效显著。
Objective To investigate the efficacy of ambroxol hydrochloride combined with ipratropium bromide in the treatment of bronchiolitis. Methods Seventy patients with bronchiolitis were randomly divided into control group and treatment group (n = 35). Both groups were given anti-inflammatory and antiasthmatic conventional symptomatic treatment. The control group was given dexamethasone and ribavirin inhalation, In the treatment group, ambroxol hydrochloride and ipratropium bromide were given to inhalation therapy on the basis of routine treatment, and the curative effect was observed after treatment. Results The total effective rates of the control group and the treatment group were 74.28% and 94.29%, respectively. The differences between the two groups were statistically significant. The fever, cough, wheeze disappearance and hospital stay in the treatment group were significantly shorter than those in the control group (P <0.05) . Conclusion Ambroxol hydrochloride combined with ipratropium bromide inhalation for the treatment of bronchiolitis can quickly improve the symptoms and shorten the course of the disease, and the curative effect is remarkable.