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本文报道1981～1987年,经手术切除和病理切片证实的7例胰岛素瘤病例。我们体会到最简单的诊断方法是证明Whipple氏三联征的存在,其他的方法有血浆胰岛素的测定,这种方法能精确地诊断和鉴别由于其他原因引起的低血糖病而没有危险性。外科治疗的困难是手术中难以找到肿瘤。大多数肿瘤能摘除,但是多发性的和在胰腺深部的肿瘤,必须在手术中作好解剖定位,可以减少盲目性的胰大部切除。用术中B超的方法比血管造影、CT和经皮肝门静脉插管测定门静脉、脾静脉和肠系膜上静脉内的血浆胰岛素要简单可靠。
This article reports 1978 to 1987, 7 cases of insulinoma confirmed by surgical resection and pathological section. We understand that the simplest diagnostic method is to prove the existence of Whipple’s triad, and other methods are the determination of plasma insulin. This method can accurately diagnose and identify hypoglycemia caused by other causes without risk. The difficulty in surgical treatment is that it is difficult to find a tumor during surgery. Most tumors can be removed, but multiple and deep pancreatic tumors must be anatomically located during surgery to reduce blinding pancreatic resection. Intraoperative B-mode ultrasonography is simpler and more reliable than angiography, CT, and percutaneous portal vein cannulation to measure plasma insulin in the portal vein, splenic vein, and superior mesenteric vein.