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胃癌是我国常见的恶性肿瘤之一 ,占消化道恶性肿瘤第一位 ,癌细胞侵袭和转移是影响其疗效的主要原因。胃癌侵袭和转移的过程非常复杂 ,从分子水平可将其归纳为:粘附分子介导癌细胞与正常细胞、细胞外基质(ECM)进行粘附 ;癌细胞释放多种蛋白水解酶降解所粘附的组织 ;水解?
Gastric cancer is one of the most common malignancies in China, accounting for the first place in the digestive tract malignancy. The invasion and metastasis of cancer cells are the main reasons affecting its efficacy. The process of invasion and metastasis of gastric cancer is very complex. From the molecular level, it can be summarized as follows: Adhesion molecules mediate the adhesion of cancer cells to normal cells and extracellular matrix (ECM); cancer cells release a variety of proteolytic enzymes to degrade their adhesion Attached tissue; hydrolysis?