论文部分内容阅读
目的 研究阿托伐他汀对糖尿病并发高脂血症患者降脂的疗效。方法 选择我院门诊及住院153 例糖尿病并发高脂血症患者,男85例,女68例。用药前停用其它降脂药,并进行TC、TG、HDL-C、LDL-C、 ACT、AST、CK化验和饮食控制。阿托伐他汀20mg每日1次,治疗6周后重复上述化验检查。结果 治疗前后 TG、TC和LDL-C分别较治疗前显著下降,P<0.001。降低程度分别达37.4%,26.9%,29.7%。HDL-C治疗 后明显升高,上升率16.8%,P<0.001。ACT、AST和CK治疗前后无明显差别,P>0.05。结论 阿托伐他汀 对糖尿病合并高脂血症有明显降脂作用。
Objective To study the effect of atorvastatin on lipid-lowering in patients with diabetes and hyperlipidemia. Methods 153 outpatients and hospitalized patients with diabetes mellitus and hyperlipidemia were selected, including 85 males and 68 females. Stop using other lipid-lowering drugs before treatment, and TC, TG, HDL-C, LDL-C, ACT, AST, CK test and diet control. Atorvastatin 20mg once daily, 6 weeks after treatment, repeat the above laboratory tests. Results The levels of TG, TC and LDL-C before and after treatment were significantly lower than those before treatment (P <0.001). The reduction was 37.4%, 26.9% and 29.7% respectively. After HDL-C treatment was significantly higher, the rate of increase of 16.8%, P <0.001. ACT, AST and CK no significant difference between before and after treatment, P> 0.05. Conclusions Atorvastatin has a significant lipid-lowering effect on diabetic hyperlipidemia.