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目的观察国产美罗培南在恶性血液病化疗后导致中性粒细胞减少的伴发感染治疗效果。方法回顾性分析2008年8月至2011年8月期间在我院血液科住院的恶性血液病患者180例,化疗后合并感染,应用国产美罗培南抗感染的疗效和不良反应。结果 180例患者中,有效率为75%(135/180),不良反应率为4.4%(8/180)。结论国产美罗培南在治疗恶性血液病合并感染安全有效。
Objective To observe the effect of domestic meropenem in the treatment of concomitant infection that leads to neutropenia after chemotherapy of hematologic malignancies. Methods A retrospective analysis of 180 patients with hematologic malignancies hospitalized in our department of hematology between August 2008 and August 2011 was performed. After chemotherapy, the patients were treated with anti-infection and the adverse reactions were retrospectively analyzed. Results Among the 180 patients, the effective rate was 75% (135/180) and the adverse reaction rate was 4.4% (8/180). Conclusion Domestic Meropenem is safe and effective in the treatment of co-infection of hematologic malignancies.