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为了解“脑康”（由白蒺藜全草中提取的３个有效成分为主组成）对动脉粥样硬化（ＡＳ）的作用机理，采用高血脂兔ＡＳ模型，观察其对血脂（血清胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白）、血液流变学（全血比粘度、血浆粘度）、血小板聚集、纤维蛋白原、血浆血栓素Ｂ２、前列环素ＰＧＦ１α和动脉病理形态的影响，并与银杏胶囊作对比。结果提示：脑康通过降低血脂、改善血液流变学、抑制血小板聚集、调节血栓素Ｂ２和前列环素ＰＧＦ１α平衡等多途径干预ＡＳ的发生、发展，并可能促使ＡＳ的消退，疗效优于银杏胶囊。
In order to understand the mechanism of “brain health” (the three active components extracted from the whole plant of Paeonia lactiflora) on atherosclerosis (AS), a model of hyperlipidemia rabbit AS was used to observe its effects on serum lipids (serum cholesterol, Triglyceride, high-density lipoprotein, low-density lipoprotein), hemorheology (specific viscosity of whole blood, plasma viscosity), platelet aggregation, fibrinogen, plasma thromboxane B2, prostacyclin PGF1α, and arterial pathological morphology Influence and contrast with ginkgo capsules. The results suggest that Naokang interferes with the occurrence and development of AS by lowering blood lipids, improving hemorheology, inhibiting platelet aggregation, regulating the balance of thromboxane B2 and prostacyclin PGF1α, and may promote the regression of AS, which is superior to Ginkgo biloba. capsule.