瘿消颗粒剂的药效学研究

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正常小鼠po瘿消颗粒剂20d后,使小鼠机体耗氧量明显低于正常对照组,效果与他巴唑相同,瘿消颗粒剂对实验性甲状腺机能亢进家兔的体重、体温、心率、心电图、血清T3、T4值等各项指标均有明显改善,并使甲 功能和形态基本恢复正常,它还可使正常大鼠血清T4值下降,其作用与他巴唑相似,说明该方剂有明显抗甲状腺机能亢进作用。
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