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目的:观察抗生素联合中药治疗湿热瘀结型盆腔炎的临床疗效。方法:采用随机双盲法将100例湿热瘀结型盆腔炎患者分为对照组与治疗组各50例,对照组采取常规抗生素治疗,治疗组在对照组基础上联合中药内服与保留灌肠治疗,比较2组的临床疗效、治疗前后中医证候积分、局部体征(子宫活动受限及压痛、单侧或双侧附件包块)的改善及不良反应情况。结果:总有效率治疗组为94.0%,对照组为80.0%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组中医证候总积分均较治疗前下降,差异均有统计学意义(P<0.05);治疗组中医证候总积分明显低于对照组(P<0.05)。治疗后,治疗组子宫活动受限及压痛、单侧附件包块及双侧附件包块比率均低于治疗前,并优于对照组治疗后,差异均有统计学意义(P<0.05)。结论:抗生素联合中药治疗湿热瘀结型盆腔炎安全有效,能明显改善下腹坠痛、附件包块等症状及局部体征。
Objective: To observe the clinical efficacy of antibiotics combined with traditional Chinese medicine in the treatment of damp-heat stasis type pelvic inflammatory disease. Methods: A total of 100 patients with hydrothermal stasis tuberculous pelvic inflammatory disease were divided into control group and treatment group by randomized double-blind method. The control group was treated with conventional antibiotics. The treatment group was treated with traditional Chinese medicine and retention enema on the basis of the control group. The clinical curative effect, TCM syndrome score before and after treatment, local signs (restricted uterine movement and tenderness, unilateral or bilateral attachment mass) and adverse reactions were compared between the two groups. Results: The total effective rate was 94.0% in the treatment group and 80.0% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the total scores of TCM syndromes in both groups were significantly lower than those before treatment (P <0.05). The total score of TCM syndromes in the treatment group was significantly lower than that in the control group (P <0.05). After treatment, the uterus in the treatment group had limited activities and tenderness. The rates of unilateral accessory mass and bilateral accessory mass were lower than those before treatment and better than that of the control group (P <0.05). Conclusion: Antibiotics combined with traditional Chinese medicine is safe and effective in treating damp-heat stasis type pelvic inflammatory disease, and can significantly improve the symptoms and local signs of lower abdomen pain and accessory mass.