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目的回顾总结甘油冷冻保存角膜用于穿透性角膜移植（ＰＫＰ）的临床效果。方法９个新鲜供体眼球分３种方法进行甘油冷冻保存６～３４９天后，对９例重症角膜患者进行了穿透性角膜移植术，随访６～２３个月并记录临床效果。结果全部手术获得成功，７７．８％（７／９）的角膜植片获得透明愈合，内皮细胞密度达１４００个／ｍｍ２。植片混浊的２例患者也得以保存眼球，其中１例更换植片后获得良好视力。结论甘油冷冻保存角膜可能是一种极具前途的角膜活性保存方法。
Objective To review the clinical effects of glycerol cryopreservation on penetrating keratoplasty (PKP). Methods Nine fresh donor eyes were cryopreserved in 3 ways for 6 to 349 days. Penetrating keratoplasty was performed on 9 patients with severe corneas. The patients were followed up for 6 to 23 months and the clinical effects were recorded. Results All surgeries were successful. 77.8% (7/9) of the corneal grafts were healed transparently and the endothelial cell density reached 1400 / mm2. Two patients with opacified ophthalmology were also able to preserve the eyeball, one of whom had good visual acuity after replacement of the implant. Conclusion Cryopreservation of cornea with glycerol may be a promising method of preserving corneal activity.