Evaluation the effect of fertility-preserving surgery on young patients with malignant ovarian tumor

来源 :The Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:xueliping
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Objection:To evaluate the impact of fertility-preserving surgery and adjuvant chemotherapy on survival and fertility of young patients with ovarian malignant tumors.Methods:Retrospective analysis of 39 patients with ovarian malignant germ cell tumors,23 patients with malignant epithelial tumors and 4 patients with sexual cord mesenchymal tumors receiving conser-vative treatments.Results:Two patients lost follow-up(we do not statistics them).Fifty-nine among 64 patients were alive up to now(92.19%).The overall survival rate for ovarian epithelial malignancies,malignant germ cell tumors and sexual cord mes-enchymal tumors were 95.45%,89.47% and 100% respectively.Fifteen patients received second operation and recurrence was found in 6 patients.Among the 59 surviving patients,53 patients have normal menstruation.Thirteen patients among 20 patients who want to pregnant have 15 pregnancies and 9 successful deliveries.Conclusion:The management of fertility-preserving surgery on patients with ovarian malignant germ cell tumors,whatever the FIGO staging is,is a safe option.For patients with ovarian epithelial carcinomas,fertility-preserving surgery only confined to low-stage(stage I),low-grade(G1),and patients who want keep fertility function seriously.Cisplatinum-based combination chemotherapy is necessary.Standardized chemotherapy has no affection on fertility function. Objection: To evaluate the impact of fertility-preserving surgery and adjuvant chemotherapy on survival and fertility of young patients with ovarian malignant tumors. Methods: Retrospective analysis of 39 patients with ovarian malignant germ cell tumors, 23 patients with malignant epithelial tumors and 4 patients with Of the two patients who lost follow-up (we do not statistics them) .Fifty-nine among 64 patients were alive up to now (92.19%). The overall survival rate for ovarian epithelial malignancies , malignant germ cell tumors and sexual cord mes-enchymal tumors were 95.45%, 89.47% and 100% respectively. Patients receiving second operation and recurrence was found in 6 patients. Am I the 59 surviving patients, 53 patients have normal menstruation.Thirteen patients among 20 patients who want to pregnant have 15 pregnancies and 9 successful deliveries. Confluence: The management of fertility-preserving surgery on patients with patients ovarian malignant germ cell tumors, whatever the FIGO staging is, is a safe option. Patients with ovarian epithelial carcinomas, fertility-preserving surgery only confined to low-stage (stage I), low-grade (Gl), and patients who want keep fertility function seriously. Discoid-based combination chemotherapy is necessary. There is no affection on fertility function.
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