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本文对28例急性三硝基甲苯中毒患者及相配对的28例年龄、性别相同的不接触任何毒物的健康对照人员进行了血清谷丙转氨酶,谷草转氨酶和血清总蛋白、白蛋白和球蛋白分析。同时对患者进行了B超、心电图检查。结果表明:患者血清谷丙转氨酶和谷草转氨酶较对照组显著升高(P<0.01);但血清总蛋白、白蛋白和球蛋白含量与对照组相比未见明显下降;B超和心电图结果也显示三硝基甲苯对肝脏和心脏有一定损害。因此,初步认为血清谷丙转氨酶和谷草转氨酶可作为急性三硝基甲苯中毒致肝损伤的较好的检测指标。
In this paper, 28 cases of acute TNT patients and matched 28 cases of age, gender, do not contact with any of the poison of healthy controls serum alanine aminotransferase, serum total protein, albumin and globulin analysis . At the same time the patient was B ultrasound, ECG. The results showed that serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in patients were significantly higher than those in control group (P <0.01), but serum total protein, albumin and globulin contents were not significantly decreased compared with control group; Trinitrotoluene also showed some damage to the liver and heart. Therefore, it is initially believed that serum alanine aminotransferase and aspartate aminotransferase can be used as a good indicator of liver damage caused by acute trinitrotoluene poisoning.