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目的探讨高频震荡通气(HFOV)治疗早产儿呼吸窘迫综合征(NRDS)的临床效果。方法 57例早产NRDS患儿,30例接受HFOV治疗为HFOV组,27例接受常频机械通气(CMV)治疗为CMV组。分析比较两组疗效。结果治疗后HFOV组氧合指数(OI)、氧分压(PaO_2)、二氧化碳分压(PaCO_2)改善情况明显优于CMV组(P<0.05);HFOV组总有效率90.00%明显高于CMV组的74.07%(P<0.05)。结论 HFOV治疗早产儿NRDS疗效及安全性均值得信赖,极具临床应用价值。
Objective To investigate the clinical effect of high frequency oscillatory ventilation (HFOV) on respiratory distress syndrome (NRDS) in preterm infants. Methods Fifty-seven children with premature NRDS, 30 HFOV patients and 27 CMV patients were treated with CMV. Analysis and comparison of two groups efficacy. Results The improvement of oxygenation index (OI), oxygen partial pressure (PaO_2) and partial pressure of carbon dioxide (PaCO_2) in HFOV group was significantly better than that in CMV group (P <0.05). The total effective rate in HFOV group was significantly higher than that in CMV group Of 74.07% (P <0.05). Conclusion The efficacy and safety of HFOV in the treatment of NRDS in preterm infants are trustworthy and have clinical value.