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应用替硝唑片口服治疗40例冠周炎、牙周炎患者,以甲硝唑为对照检测了治疗前后冠周盲袋及牙周袋内厌氧菌的变化。结果表明,服用替硝唑后,袋内厌氧菌的数量及种类明显下降,而球菌的数量明显增多。替硝唑治疗冠周炎、牙周炎的疗效(92.5%)优于甲硝唑(65.0%)。替硝唑对冠周袋及牙周袋的厌氧菌杀灭强度及速度较甲硝唑好,特别是对产黑色素G-厌氧杆菌,不产黑色素G-厌氧杆菌,小韦荣氏菌,CO2噬纤维菌具有很强的杀灭效果。
40 cases of pericoronitis and periodontitis were treated with tinidazole tablets orally, and the change of anaerobic bacteria in the periorbital blind pocket and periodontal pocket was measured with metronidazole as control before and after treatment. The results showed that after taking tinidazole, the number and type of anaerobic bacteria in the bag decreased significantly, but the number of cocci increased obviously. Tinidazole treatment of pericoronitis, periodontitis efficacy (92.5%) is better than metronidazole (65.0%). Antimicrobial effect of tinidazole on perivascular bags and periodontal pockets was better than that of metronidazole, especially for the production of melanin G-anaerobes, melanin-free anaerobic bacilli, Bacteria, CO2 phage bacteria have a strong killing effect.