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目的探讨爱活尿通对人类精液液化时间延长者的治疗效果,同步检测治疗前后精液中凝血因子的变化。方法 46例精液液化时间延长者口服爱活尿通为治疗组,2周后复查精液液化时间,同时检测治疗前后精液中组织因子(TF)、凝血因子Ⅶa(F Ⅶa)及凝血因子ⅧAg(F Ⅷ Ag)含量。45例精液常规正常者作为对照组。结果经治疗,32例液化时间<30 min,占70%,12例液化时间在30至60 min之间,占26%,2例液化时间仍大于60 min,占4%,较治疗前液化时间缩短,且精子活力提高,差异有显著性(P<0.05);治疗后精液中TF、F Ⅶ a及FⅧ Ag含量降低(P<0.05),与对照组相比无统计学意义(P>0.05)。结论爱活尿通对精液液化时间延长者有一定疗效;对影响精液液化的凝血因子水平可能具有改善作用。
Objective To explore the therapeutic effect of loving urinary tract on human semen liquefaction time, and to detect the changes of coagulation factors in semen before and after treatment. Methods Forty - six patients with prolonged semen liquefaction were treated with oral dextromethorphan. After two weeks, the semen liquefaction time was examined. Tissue factor (TF), coagulation factor Ⅶ a (F Ⅶ a) and coagulation factor Ⅷ Ag Ⅷ Ag) content. 45 cases of normal normal semen as a control group. Results After treatment, the liquefaction time of 32 patients was less than 30 minutes, accounting for 70%. The liquefaction time of 12 patients was between 30 and 60 minutes, accounting for 26%. The liquefaction time was still longer than 60 minutes, accounting for 4% (P <0.05). After treatment, the content of TF, F Ⅶ a and FⅧ Ag in semen decreased (P <0.05), but there was no significant difference between the two groups ). Conclusion Aihuitong has some curative effect on semen liquefaction time; it may have an effect on the level of blood coagulation factors affecting semen liquefaction.