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目的比较高龄患者在药物洗脱支架(DES)和金属裸支架(BMS)植入后出血并发症的发生率,探讨高龄患者支架的选择问题。方法2004年5月～2006年5月收治经皮冠脉介入治疗(PCI)年龄>75岁的冠心病患者360例,其中DES植入196例,BMS植入164例。术后按常规服药,随访1年。术后1,3,6及12个月复查血、尿常规、粪隐血,观察有无出血情况。结果两组患者在性别、年龄、并发症及病变程度方面无明显差异。1年内DES组47例出现出血,出血并发症明显增多,而BMS组出血13例,且两组比较有统计学差异(P<0.01)。结论高龄患者DES植入术后出血率增加。
Objective To compare the incidence of bleeding complications in elderly patients after implantation of drug-eluting stent (DES) and bare metal stent (BMS), and to explore the selection of stent in elderly patients. Methods From May 2004 to May 2006, 360 patients with coronary heart disease undergoing percutaneous coronary intervention (PCI)> 75 years of age were enrolled, of whom 196 were DES and 164 were BMS. Postoperative routine medication, follow-up 1 year. Postoperative 1, 3, 6 and 12 months review of blood, urine, fecal occult blood, observe the presence of bleeding. Results There was no significant difference in gender, age, complications and degree of disease between the two groups. Bleeding was found in 47 cases in DES group in one year, bleeding complications were significantly increased, while in BMS group, 13 cases were hemorrhage, with statistical difference (P <0.01). Conclusion Bleeding rate in elderly patients with DES implantation increases.