卡铂是第二代铂类抗癌药,近年来因其肾耳毒性少等优越性而引起人们的高度重视。卡铂的实验研究已见有多篇报道,但卡铂与顺铂严格的疗效比较以及不同给药途径与不同给药方案可能对疗效所产生的影响,国内外文献的报道尚不多。本文对这些方面作了较详尽的实验比较,现报告如下。材料与方法一、药物卡铂为白色粉状物,顺铂为黄色粉状物,昆明贵金属研究所合成,用5%葡萄糖液溶解 Carboplatin is a second-generation platinum anticancer drug. In recent years, it has attracted people’s attention due to its superiority of less-kidney ototoxicity. Carboplatin has been reported in many experiments, but the strict efficacy of carboplatin and cisplatin and different routes of administration and different dosing regimens may have an impact on efficacy. There are not many domestic and foreign reports. This article has made more detailed experiments comparing these aspects. The report is as follows. Materials and Methods 1. The drug carboplatin was a white powder and cisplatin was a yellow powder. It was synthesized by Kunming Institute of Precious Metals and dissolved in 5% glucose solution.