论文部分内容阅读
在糖尿病的发展过程中,可导致全身多系统和多脏器的损害,发生各种并发病。病理解剖发现,糖尿病患者有半数以上可见动脉硬化,有肾小球硬化者占25～44%;据临床资料统计,糖尿病患者并发冠心病约2～3倍于非糖尿病者,发生心肌梗塞和病死率也高于非糖尿病者2～3倍。糖尿病患者易罹患感染,并发肺结核者是非糖尿病者的3～5倍。糖尿病性肾脏病和神经病变也相当多见。对有并发病的糖尿病患者,在应用降血糖药物的同时,常需并用其它药物。但降血糖药与某些药物伍用时,可发生降血糖作用增强或减弱,或副作用加重。因此,必须对有关药物的相互作用给予重视。现重点叙述于下。一、利尿药利尿药与降血糖药并用引起不良反应的发生率达13.12%,仅次于洋地黄与排钾性利尿药的并用。利
In the development of diabetes, can lead to systemic multi-system and multiple organ damage, a variety of complications. Pathological anatomy found that more than half of diabetic patients with visible atherosclerosis, with glomerular sclerosis accounted for 25 to 44%; according to clinical data, patients with coronary artery disease about 2 to 3 times the non-diabetic patients with myocardial infarction and death Rate is also higher than non-diabetic patients 2 to 3 times. Diabetes patients are susceptible to infection, complicated by pulmonary tuberculosis are non-diabetic patients 3 to 5 times. Diabetic nephropathy and neuropathy are also quite common. For patients with concurrent diabetes, hypoglycemic drugs in the application of the same time, often need to use other drugs. However, hypoglycemic agents and certain drugs Wu Wu, hypoglycemic effect may occur with increased or decreased, or worse side effects. Therefore, attention must be paid to the drug interactions. The key points are described below. First, the diuretic Diuretics and hypoglycemic agents cause adverse reactions with the incidence of 13.12%, second only to digitalis and row potassium potassium diuretics used in combination. Lee