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目的：探讨中心静脉导管胸腔置管引流在胸腔积液治疗中的应用价值。方法回顾性分析168例胸腔积液患者，随机分成两组，引流组（96例）和胸穿组（72例），引流组采用中心静脉导管行胸腔置管引流术，胸穿组使用传统胸腔穿刺术，两组年龄，病情差异无统计学意义（P>0.05），对这两组的操作过程，治疗效果及不良反应发生率进行比较。结果引流组均成功引流胸水，胸水引流彻底，操作过程患者容易耐受，呼吸困难明显缓解，无明显不良反应发生。胸穿组出现病情较重者不能耐受，胸水引流不彻底，出现胸膜反应穿刺不成功等情况。结论中心静脉导管胸腔置管引流术较传统胸腔穿刺术在胸腔积液的治疗中更安全，有效，值得临床推广。“,”objective :explore the central venous catheter chest tube drainage in the treatment of pleural effusion and application value. Method:a retrospective analysis of 268 patients with pleural effusion, and randomly divided into two groups, the treatment group (96 cases) and control group (72 cases), the treatment group with central venous catheter line of chest drainage tube, control group using traditional thoracentesis, two groups of age, there was no statistical significance (P > 0.05) difference condition and operation method of the two groups, the treatment effect, and to compare the incidence of adverse reactions. Result: the treatment group were successful drainage of pleural effusion, pleural effusion drainage thoroughly, patients with operation easy to tolerance, obviously al eviate breathing difficulties, no obvious adverse reaction occurred. In control il ness ,Patients with more severe cases cannot tolerate, pleural effusion drainage is not thorough, appeared pleural reaction puncture is not successful, and so on and so forth. Conclusion: central venous catheter pleural drainage than traditional thoracentesis tube in the treatment of pleural effusion is safe, effective, worthy of clinical promotion.