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目的探讨不孕不育与染色体核型异常的关系,指导临床诊断。方法采集1242例不孕不育咨询者外周血,进行淋巴细胞培养,常规方法收获细胞,低渗、固定、制片,经G显带处理,镜检观察染色体核型。结果 1242例不孕不育咨询者共检出异常核型139例,总异常率11.19%。结论染色体核型异常是导致不孕不育的重要原因之一,因此,对不孕不育咨询者进行染色体检查是非常必要的。
Objective To investigate the relationship between infertility and chromosomal abnormalities and to guide clinical diagnosis. Methods 1242 cases of infertility consultants were collected from peripheral blood for lymphocyte culture. Cells were harvested by conventional methods. The cells were hardened, hypotonic, fixed, prepared and treated with G - banding. The karyotypes were observed microscopically. Results A total of 1242 cases of infertility consultants were detected 139 cases of abnormal karyotype, the total abnormal rate was 11.19%. Conclusion Chromosomal abnormalities are one of the important causes of infertility. Therefore, it is necessary to carry out chromosome examination on infertility consultants.