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目的:探讨不同部位脑梗死患者急性期颈部动脉血流动力学改变及临床意义。方法:研究对象包括39例左前循环脑梗死患者、76例右前循环脑梗死患者、34例后循环脑梗死患者及59例非脑梗死患者。应用彩色多普勒超声在入院后1周内检测颈部动脉收缩期峰值流速、舒张末期流速、加速度时间、阻力指数。应用t检验或非参数检验对数据进行分析处理。结果:不同部位脑梗死患者分别与非脑梗死患者比较,双侧颈总动脉阻力指数均升高,差异有统计学意义(P<0.05);左、右前循环脑梗死患者分别与非脑梗死患者比较,双侧颈总动脉舒张末期流速均下降,差异有统计学意义(P<0.05)。结论:脑梗死患者普遍存在着双侧颈总动脉高阻力现象,这种现象与脑梗死部位、受累血管无关;脑梗死急性期保持较高平均动脉压对防止病情进展具有重要意义。
Objective: To investigate the changes of hemodynamics of neck artery in patients with acute cerebral infarction at different sites and its clinical significance. METHODS: Subjects included 39 patients with left anterior circulation cerebral infarction, 76 patients with right anterior circulation cerebral infarction, 34 patients with posterior circulation cerebral infarction and 59 non-cerebral infarction patients. Color Doppler ultrasound was used to detect peak systolic velocity, end diastolic velocity, acceleration time and resistance index of cervical artery within 1 week after admission. Apply t-test or non-parametric test to analyze the data. Results: Compared with non-cerebral infarction patients, the resistance index of bilateral common carotid arteries increased significantly in patients with cerebral infarction at different sites (P <0.05). The left and right anterior circulation cerebral infarction patients were respectively compared with non-cerebral infarction patients Compared with the control group, the end-diastolic velocity of bilateral common carotid arteries decreased, the difference was statistically significant (P <0.05). Conclusion: There is a common phenomenon of high resistance to bilateral common carotid arteries in patients with cerebral infarction. This phenomenon has nothing to do with the site of cerebral infarction and vascular involvement. It is of great importance to maintain high mean arterial pressure during the acute phase of cerebral infarction to prevent the progression of the disease.