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临床资料患者,女,22岁,因同居未避孕未孕2年就诊。月经初潮15岁,月经周期4~5 d/28~32 d,孕0产0。外院监测卵泡4个周期,均有优势卵泡生长及排卵,均未受孕,丈夫重度少弱畸精症,拟经皮穿刺附睾取精术(percutaneous epididymal sperm extraction,PESA )结合卵细胞浆内单精子注射(Intracytoplasmic sperm injection,ICSI )助孕治疗。查基础内分泌:雌二醇(estradiol,E2)31715 ng/L,催乳素(prolac