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目的:优选妇康胶囊的最佳提取工艺。方法:采用正交试验设计,分别以蛇床子素、盐酸小檗碱提取率和浸膏收率为指标,优化黄连、蛇床子等6味药材的提取工艺;以没食子酸提取率和浸膏收率为指标,优选没食子等4味药材的提取工艺。结果:6味药材最佳提取工艺为:10倍量70%乙醇回流提取2次,每次1 h;没食子等4味药材最佳提取工艺为:10倍量水煎煮3次,每次1 h;结论:优选的提取工艺稳定、可行。
Objective: To optimize the extraction process of Fukang capsule. METHODS: Orthogonal design was used to optimize the extraction process of six herbs, such as Coptis chinensis Franch and Fructus Cnicae, with the extraction rate of osmanthrin and berberine, Rate as an indicator, preferably gallop 4 herbs extraction process. Results: The optimal extraction process of six herbs was as follows: 10 times the amount of 70% ethanol reflux extraction 2 times, each time 1 h; 4 herbs such as gallbladder the best extraction process: 10 times the amount of boiling water 3 times, each time 1 h; Conclusion: The optimal extraction process is stable and feasible.