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目的 观察鼻咽癌外照射联合高剂量率腔内后装治疗的近期疗效和反应。从 1996年 8月至 1998年 8月 ,74例鼻咽癌患者中 ,16例早期鼻咽癌外照射DT52 6 2GY 5 2 6 2W ,腔内治疗DT16 2 4GY 2 3W 2 3T ,38例外照射DT70GY 7W后 ,鼻咽肿块残存 ,加腔内治疗DT6 16GY 1 2W 1 2T ,2 0例局部复发外照射DT4 0 6 0GY 4 6W后 ,腔内治疗DT16 30GY 2 3W 2 3T。结果 腔内治疗剂量大于 2 4GY和复发再治者粘膜反应较重 ,局部残存者消退率 10 0 % ,局部复发再治消退率 90 % ,1年局部控制率 93 3%。结论 适当的腔内治疗可提高局部消退率和控制率 ,且无严重的并发症发生。
Objective To observe the short-term curative effect and response of nasopharyngeal carcinoma external beam combined with high dose rate intracavity afterloading treatment. From August 1996 to August 1998, 74 patients with nasopharyngeal carcinoma, 16 cases of early nasopharyngeal carcinoma outside the irradiation DT52 6 2GY 5 2 6 2W, endovascular treatment of DT16 2 4GY 2 3W 2 3T, 38 cases of external irradiation DT70GY After 7 weeks, the nasopharyngeal tumor was remnant, and treated with lumen DT6 16GY 1 2W 1 2T, 20 cases of local recurrence of external radiation DT 4 0 6 0GY 4 6W, and endoluminized with DT16 30GY 2 3W 2 3T. Results The intraluminal therapeutic dose was more than 2 4GY and the mucosal reaction was more severe in relapsed and re-treated patients. The local residual rate of remission was 10%. The local recurrence and remission rate was 90% and the local control rate was 93.3%. Conclusion The appropriate endovascular treatment can improve the local rate of regression and control, and no serious complications.