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158例肾病综合征中,治愈84例(53.2%),完全缓解24例(15%)。死亡39例,病死率24.6%。开始对激素治疗敏感者预后良好。激素疗程短者易复发,若延长疗程,积极控制感染,仍可获治愈和完全缓解。对激素治疗反应差者,应合并免疫抑制剂治疗。死亡多发生在病后2年内,主要原因为感染,而肾功能衰竭极少。如能控制感染,减少复发,病程达2年以上者则预后较好。治疗中应重视高凝状态及高脂血症所引起的并发症。
Of the 158 nephrotic syndromes, 84 (53.2%) were cured and 24 (15%) were completely relieved. 39 cases died, the fatality rate was 24.6%. Sensitivity to hormone therapy began with a good prognosis. Short duration of hormone therapy is easy to relapse, if prolonged course of treatment, and actively control the infection, can still be cured and completely relieved. Poor response to hormone therapy should be combined with immunosuppressive therapy. Death occurred more than 2 years after the disease, the main reason is infection, and very few renal failure. If you can control the infection, reduce recurrence, duration of more than 2 years, the prognosis is better. Treatment should pay attention to hypercoagulable state and complications caused by hyperlipidemia.