【摘 要】
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The success rate and multiple pregnancy rate are two important issues emerging in assisted reproductive technology cycles [1].It is usually used to increase the
【机 构】
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Shanghai Ji Ai Genetics & IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shang
论文部分内容阅读
The success rate and multiple pregnancy rate are two important issues emerging in assisted reproductive technology cycles [1].It is usually used to increase the number of embryos;however,it increases the risk of multiple pregnancies.Therefore,the key point to improve the success rate is to select the best-quality embryos [2-4].Currently,noninvasive embryo selection emerges which is primarily based on morphological criteria,such as pronuclear morphology [5-7],appearance of much fragmentation [8-11],and multinucleation of blastomeres [12] and unequal-sized blastomeres [13-16] by light microscopy analysis.Although it is easy and convenient to obtain data by using these morphological criteria which are known to contribute to pregnancy outcomes,they have limited predictive value for ongoing pregnancy and the accuracy to select embryos of high reproductive potential almost depends on the experience of embryologist [17-19].Therefore,new selection techniques are needed [20,21].
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