药理学米多君(Midodrine)是一个强力的、选择性作用于外周α-受体的激动剂,但至今尚未明了它主要是作用于α_1-受体还是作用于α_2-受体。口服或静注本品后可使健康志愿者的卧位或立位血压适度提高。对直立性低血压患者能显著地升高血压,减少静脉容量(即增加静脉张力)和减少卧位和立位心率。米多君引起外周血管阻力的增强是使低 Pharmacology Midodrine is a potent and selective agonist of peripheral α-receptors, but it has not yet been clarified whether it acts predominantly on α 1 -receptors or on α 2 -receptors. Oral or intravenous injection of this product can make healthy volunteers supine or standing blood pressure modest increase. In patients with orthostatic hypotension can significantly increase blood pressure, reduce venous capacity (ie increased venous tension) and reduce supine and upright heart rate. Midodrine causes peripheral vascular resistance enhancement is low