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已知用IUD妇女可发生以自发性流产告终的妊娠,但对置环后月经规则的妇女是否会发生早期胚胎着床有不同的意见。本文中作者测定了42例置IUD后有规则行经妇女黄体晚期血中SP_1和β-hCG水平,以观察置IUD妇女自发性流产发生率并与未采用避孕措施的妇女进行比较。参与研究的妇女24～45岁,3例产次为0(其中2例曾有较早期自发性流产史),8例产次1,24例产次2,7例产次3～4次。42例中共有7次早期自发性流产史,12例有合法的人流史,所有对象均有性生活,无不育问题,41例用CuT200IUD,1例用Lippes LoopD IUD,置环2～37个月,置环后月经规则,间隔25～30天,在研究的73个周期中每周期取血1～3次,其中1例共随访17个周期,42例共取血129个样品,用RIA测血中SP_1和β-hCG水平,测定的阈值分别为1μg/l和3IU/l。
It is known that pregnancy with spontaneous abortion can occur in women with IUD, but there are different opinions as to whether women with menstrual cycle rules have early embryo implantation. In this paper, we measured the levels of SP_1 and β-hCG in women with luteal phase after 42 IUDs were set to observe the incidence of spontaneous abortion in women with IUD and compared with women without contraception. The women participating in the study ranged in age from 24 to 45 years, 3 were 0 (2 had an earlier history of spontaneous abortion), 8 were given 1, 24 were given 2, and 7 were given 3 to 4 times. 42 cases of a total of seven times the history of early spontaneous abortion, 12 patients with a history of legal history, all subjects have sex life, no problems of infertility, 41 cases with CuT200IUD, 1 case with Lippes LoopD IUD, ring 2 to 37 months , After ring set the rules of menstruation, 25 to 30 days interval, in the study of 73 cycles of blood per cycle 1 to 3 times, of which 1 case were followed up for a total of 17 cycles, 42 samples taken a total of 129 samples with RIA Blood levels of SP_1 and β-hCG were measured at 1 μg / l and 3 IU / l, respectively.