[目的]探讨大肝癌切除术后并用双插管化疗对预防术后复发的作用。[方法]1989年～1996年 ,我们对76例原发性肝癌切除术后病例施行了经肝动脉、门静脉双插管化疗 ,67例行单纯手术切除。[结果]插管化疗组的1、2、3年复发率比对照组低10 %以上。[结论]原发性肝癌切除术后行双插管化疗是预防术后复发的有效方法。 [Objective] To investigate the effect of double intubation chemotherapy on the prevention of postoperative recurrence after hepatocellular carcinoma resection. [Methods] From 1989 to 1996, we performed dual hepatic artery and portal vein chemotherapy in 76 cases of primary liver cancer after resection, and 67 cases underwent surgical resection alone. [Results] The recurrence rate in the intubation chemotherapy group at 1, 2 and 3 years was lower than that of the control group by more than 10%. [Conclusion] Double intubation chemotherapy after resection of primary hepatocellular carcinoma is an effective method to prevent postoperative recurrence.