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甘露醇致急性肾功能衰竭称为甘露醇性肾病。临床上并不罕见,且预后严重,尤其是脑卒中病人。现报告脑卒中老年人甘露醇性肾病38例,分析其临床特点,以便更好地预防与治疗。 1 资料与方法 1.1 一般资料:分析1990年1月～1998年1月住院有使用甘露醇的脑卒中老年病人416例。各例在积极治疗原发病及其合并症的同时每日静脉滴注甘露醇75～300g,3～10天后(平均5.2天)发生甘露醇性肾病。共发现甘露醇性肾病38例,其中男23例,女15例,年龄60～92岁,平均年龄68岁,脑
Mannitol-induced acute renal failure is called mannitol nephropathy. Clinical is not uncommon, and the prognosis is serious, especially stroke patients. Now reported 38 cases of stroke in elderly mannitol nephropathy, analysis of its clinical features, in order to better prevent and treat. 1 Materials and Methods 1.1 General Information: Analysis of January 1990 ~ January 1998 hospitalized elderly patients with mannitol in stroke in 416 cases. Cases of active treatment of primary disease and its complications at the same time daily intravenous infusion of mannitol 75 ~ 300g, 3 to 10 days (average 5.2 days) mannitol nephropathy. A total of 38 cases of mannitol nephropathy were found, of which 23 were males and 15 females, aged 60 to 92 years, mean age 68 years, brain