我们近年来观察到5例骨髓增生异常综合征(MDS)转为白血病。现报告如下。 临床资料 5例中男4例,女1例;年龄4～5岁4例,10岁1例。出现症状到确诊为白血病时间2.5～4月,平均3.7月。转变的白血病类型为急淋、急粒单各2例,急单1例。主要症状体征:长期发热、苍白、出血倾向各4例,乏力、骨关节疼痛各3例。主要实验室检查:血白细胞减少5例(1.2～3.6×10~9/L),难治性贫血4例(42～77g/L),血小板减 In recent years, we have observed 5 cases of myelodysplastic syndrome (MDS) to leukemia. The report is as follows. 5 cases of clinical data in 4 males and 1 females; 4 to 5 years old in 4 cases, 10 years old in 1 case. Symptoms to the diagnosis of leukemia time 2.5 months, an average of 3.7 months. The type of acute leukemia changed acute pellet single in 2 cases, 1 case of urgent orders. The main symptoms and signs: long-term fever, pale, bleeding tendency in 4 cases, fatigue, bone and joint pain in 3 cases. The main laboratory tests: 5 cases of leukopenia (1.2 ~ 3.6 × 10 ~ 9 / L), refractory anemia in 4 cases (42 ~ 77g / L), thrombocytopenia