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目的:探讨治疗念珠菌外阴阴道炎(VVC)的适合方法。方法:对我院2007年10月~2009年10月门诊初诊为念珠菌性阴道炎的患者应用达克宁+氟康唑片治疗216例,采用回顾性分析。病患随机分为两组,A组给予氟康唑口服+达克宁阴道用药。B组采用上述治疗后于每月月经前1d口服氟康唑0.36mg。结果:A组治愈率87.2%,复发率41.2%;B组治愈率87.8%,复发率10.3%,两组的治愈率差异无统计学意义(P>0.05),复发率差异有显著统计学意义(P<0.01)。结论:结合口服+阴道抗真菌治疗后巩固治疗可明显降低复发率。
Objective: To explore a suitable method for the treatment of candida vulvovaginitis (VVC). Methods: A total of 216 patients were treated with doxene and fluconazole tablets in our hospital from October 2007 to October 2009. The patients were retrospectively analyzed. Patients were randomly divided into two groups, A group given oral fluconazole + Dacron vaginal medication. In group B, fluconazole 0.36 mg was administered 1 d before menstruation each month after the above treatment. Results: The cure rate of group A was 87.2% and the recurrence rate was 41.2%. The cure rate of group B was 87.8% and the recurrence rate was 10.3%. There was no significant difference in cure rate between the two groups (P> 0.05) (P <0.01). Conclusion: Consolidation treatment combined with oral + vaginal antifungal therapy can significantly reduce the recurrence rate.