An ever increasing demand for new lead compounds in the pharmaceutical industry has led scientists to search for natural bioactive products.Based on this extens
Glioblastomas are characterized by an aggressive local growth pattern,a marked degree of invasiveness and poor prognosis.Tumor invasiveness is facilitated by th
Ductal carcinoma in situ(DCIS)is a non-obligate precursor of invasive breast cancer with a variable biological behavior which is difficult to accurately predict
Recently,there has been significant progress in the development of genetically-engineered mouse(GEM)models.By introducing genetic alterations and/or signaling a
Pancreatic adenocarcinoma is the fourth leading cause of cancer mortality in the United States in both men and women,with a 5-year survival rate of less than 5%
E3 ubiquitin ligases are a large family of proteins that catalyze the ubiquitination of many protein substrates for targeted degradation by the 26S proteasome.T
Pneumonia and acute respiratory distress syndrome are common and important causes of respiratory failure in the intensive care unit with a significant impact on