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氯波必利对大鼠及豚鼠离体胃肠道平滑肌呈低浓度（７５～２５０ｍｇ／Ｌ）兴奋、高浓度（７５０ｍｇ／Ｌ）抑制的双相作用。在整体情况下，ｉｇ０．８～５ｍｇ／ｋｇ氯波必利可明显增强小鼠胃排空和肠推进性蠕动，只是大剂量（５ｍｇ／ｋｇ）用药早期可见胃肠活动的一过性抑制。
Clopidogrel on rats and guinea pig in vitro gastrointestinal smooth muscle was low concentration (75 ~ 250mg / L) excited, high concentration (750mg / L) inhibition of the biphasic effect. In the overall situation, ig 0.8 ~ 5mg / kg of clopidogrel can significantly enhance gastric emptying and intestinal propulsive peristalsis, only a large dose (5mg / kg) early visible gastrointestinal motility inhibition.